PMVK

Across TCGA cell cohorts, PMVK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,004 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PMVK-associated GO terms across cancer lineages are Mitochondrial transport, Negative regulation of CD8-positive, alpha-beta T cell differentiation, and Thiamine metabolic process. Each is linked with PMVK in more than 10 cancer types. Because this analysis shows association rather than direction, both PMVK-to-partner and partner-to-PMVK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial transport grouped by PMVK-low versus PMVK-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PMVK→partner) and Y-score (partner→PMVK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Mitochondrial transport →	+0.089	+0.811	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Negative regulation of CD8-positive, alpha-beta T cell differentiation →	+0.204	+0.882	<.001	<.001	3	9
PANCREAS	Thiamine metabolic process →	+1.203	+1.246	<.001	<.001	3	9
OESOPHAGUS	Mitochondrial transmembrane transport →	+0.116	+1.043	.001	.001	3	8
BREAST	Positive regulation of cytokine production involved in immune response →	-0.086	-1.274	<.001	<.001	3	8
OESOPHAGUS	DTMP catabolic process →	-0.190	-0.855	.005	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,004 associations by consensus.

Mitochondrial transport by PMVK expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →