PMS2P7

Across TCGA pan-cancer cohorts, PMS2P7 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated PMS2P7 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher PMS2P7 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PMS2P7 expression acts as an unfavorable survival marker, although some lineages such as UCS and ESCA show a favorable association.

UCS, LUAD, and ESCA are the cancer types where PMS2P7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	II,III,IV	0.657	0.257	<.001	116	view →
LUAD	DFS	Tertile	All	0.746	0.849	.003	47	view →
ESCA	OS	Median	II,III,IV	0.648	0.380	.001	35	view →
LGG	DFS	Median	All	0.778	0.884	<.001	33	view →
KICH	DFS	Quartile	All	0.610	0.963	.012	28	view →
UVM	DFS	Median	III,IV	0.294	0.821	.008	27	view →
PAAD	OS	Quartile	All	0.612	0.228	.007	18	view →
THYM	DFS	Quartile	II,III,IV	0.952	0.534	.012	18	view →
KIRC	DFS	Quartile	IV	0.372	0.712	.012	18	view →
PRAD	OS	Tertile	All	0.814	1.000	.012	16	view →
BRCA	OS	Tertile	III,IV	0.951	0.855	.003	13	view →
LAML	DFS	Quartile	All	0.590	0.289	.002	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

PMS2P7–UCS (DFS)

Open the UCS breakdown →