PMS2P6

Across TCGA patient cohorts, PMS2P6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,873 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PMS2P6-associated GO terms across cancer lineages are Regulation of chromatin organization, Protein import into peroxisome matrix, receptor recycling, and Protein desumoylation. Each is linked with PMS2P6 in more than 19 cancer types. Because this analysis shows association rather than direction, both PMS2P6-to-partner and partner-to-PMS2P6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromatin organization grouped by PMS2P6-low versus PMS2P6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PMS2P6→partner) and Y-score (partner→PMS2P6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of chromatin organization →	+0.039	+0.178	.001	<.001	3	19
THYM	Protein import into peroxisome matrix, receptor recycling →	+0.054	+0.242	.001	.003	3	19
TGCT	Protein desumoylation →	+0.053	+0.319	<.001	<.001	2	20
READ	Subtelomeric heterochromatin formation →	+0.064	+0.223	<.001	<.001	3	19
STAD	Lipoprotein biosynthetic process →	+0.036	+0.156	<.001	<.001	3	19
STAD	tRNA modification →	+0.035	+0.169	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,873 associations by consensus.

Regulation of chromatin organization by PMS2P6 expression — STAD

Explore this box plot interactively →