PMS2

Across TCGA patient cohorts, PMS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,966 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PMS2-associated proteins across cancer lineages are NUDCD3, PUS7, and FBXL18. Each is linked with PMS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both PMS2-to-partner and partner-to-PMS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMS2 versus NUDCD3 in LUAD, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PMS2→partner) and Y-score (partner→PMS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NUDCD3 →	+0.309	+0.421	<.001	<.001	3	7
HNSC	PUS7 →	+0.539	+0.362	<.001	<.001	3	6
OV	FBXL18 →	+0.325	+0.501	<.001	<.001	3	6
GBM	MLH1 →	+0.342	+0.384	<.001	<.001	3	6
PDAC	FOXK1 →	+0.348	+0.293	.002	<.001	3	6
LUAD	BAG6 →	+0.224	+0.493	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,966 associations by consensus.

PMS2 vs NUDCD3 — LUAD

Explore this scatter interactively →