PMS1

Across TCGA patient cohorts, PMS1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,752 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PMS1-associated genes across cancer lineages are NCAPD3, TMEM237, and ZNF3. Each is linked with PMS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PMS1-to-partner and partner-to-PMS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMS1 versus NCAPD3 in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PMS1→partner) and Y-score (partner→PMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NCAPD3 →	+0.419	+0.395	.008	<.001	3	4
LSCC	TMEM237 →	+0.595	+0.206	<.001	<.001	3	4
HNSC	ZNF3 →	+0.726	+0.402	<.001	<.001	3	4
HNSC	ZNF789 →	+0.986	+0.527	.002	.005	3	4
HNSC	KLHL23 →	+1.450	+0.562	<.001	.001	3	4
HNSC	LAPTM4B →	+0.758	+0.330	.008	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,752 associations by consensus.

PMS1 vs NCAPD3 — HNSC

Explore this scatter interactively →