PMPCAP1

Across TCGA patient cohorts, PMPCAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,230 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PMPCAP1-associated GO terms across cancer lineages are Regulation of chromosome organization, Negative regulation of chromosome organization, and Mitotic cytokinesis. Each is linked with PMPCAP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both PMPCAP1-to-partner and partner-to-PMPCAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome organization grouped by PMPCAP1-low versus PMPCAP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PMPCAP1→partner) and Y-score (partner→PMPCAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of chromosome organization →	+0.060	+0.158	<.001	<.001	3	13
STAD	Negative regulation of chromosome organization →	+0.056	+0.165	<.001	<.001	3	12
ESCA	Mitotic cytokinesis →	+0.074	+0.255	.002	<.001	3	12
ESCA	Chromosome localization →	+0.077	+0.127	.002	.001	3	12
STAD	Regulation of cell cycle checkpoint →	+0.054	+0.164	<.001	<.001	3	12
STAD	Positive regulation of cell cycle checkpoint →	+0.051	+0.147	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,230 associations by consensus.

Regulation of chromosome organization by PMPCAP1 expression — STAD

Explore this box plot interactively →