PMPCA

Across TCGA patient cohorts, PMPCA RNA expression is significantly associated with the protein abundance of many other proteins, with 13,492 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PMPCA-associated proteins across cancer lineages are EHMT1, TRAF2, and GTF3C4. Each is linked with PMPCA in more than 8 cancer types. Because this analysis shows association rather than direction, both PMPCA-to-partner and partner-to-PMPCA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMPCA versus EHMT1 in COAD, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PMPCA→partner) and Y-score (partner→PMPCA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	EHMT1 →	+0.355	+0.442	.002	.002	3	9
OV	TRAF2 →	+0.415	+0.664	<.001	<.001	3	7
LSCC	GTF3C4 →	+0.402	+0.460	<.001	<.001	3	7
GBM	SMC2 →	+0.535	+0.350	.001	<.001	3	6
GBM	C9orf78 →	+0.285	+0.344	<.001	<.001	3	6
OV	ECPAS →	+0.368	+0.575	.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,492 associations by consensus.

PMPCA vs EHMT1 — COAD

Explore this scatter interactively →