PMP22

Across TCGA patient cohorts, PMP22 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,807 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PMP22-associated proteins across cancer lineages are KANK2, COL6A1, and FERMT2. Each is linked with PMP22 in more than 9 cancer types. Because this analysis shows association rather than direction, both PMP22-to-partner and partner-to-PMP22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMP22 versus KANK2 in UCEC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PMP22→partner) and Y-score (partner→PMP22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KANK2 →	+0.638	+0.664	<.001	<.001	3	10
OV	COL6A1 →	+0.745	+1.059	<.001	<.001	3	10
UCEC	FERMT2 →	+0.687	+0.888	<.001	<.001	3	10
OV	RASA3 →	+0.655	+1.324	<.001	<.001	3	10
UCEC	TLN1 →	+0.419	+0.722	<.001	<.001	3	10
LSCC	ZYX →	+0.498	+0.934	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,807 associations by consensus.

PMP22 vs KANK2 — UCEC

Explore this scatter interactively →