PMP2

Across TCGA cell cohorts, PMP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,133 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PMP2-associated GO terms across cancer lineages are Late viral transcription, Protein localization to phagophore assembly site, and Cellular respiration. Each is linked with PMP2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PMP2-to-partner and partner-to-PMP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Late viral transcription grouped by PMP2-low versus PMP2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PMP2→partner) and Y-score (partner→PMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Late viral transcription →	+0.114	+0.037	<.001	.004	3	7
LUNG_NSCLC_LUSC	Protein localization to phagophore assembly site →	+0.085	+0.027	.006	.002	3	7
BREAST	Cellular respiration →	+0.064	+0.019	.001	.001	3	6
LUNG_SCLC	Lysosomal transport →	+0.047	+0.050	.008	.008	3	6
OVARY	Positive regulation of cytoplasmic translation →	+0.096	+0.026	.003	.005	1	8
LIVER	Nucleotide biosynthetic process →	+0.061	+0.028	.004	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,133 associations by consensus.

Late viral transcription by PMP2 expression — LARGE_INTESTINE

Explore this box plot interactively →