PMFBP1

Across TCGA patient cohorts, PMFBP1 protein abundance is significantly associated with the protein abundance of many other proteins, with 4,073 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PMFBP1-associated proteins across cancer lineages are MICAL3_S1649, SRRM2_S839, and MAP1S_S731. Each is linked with PMFBP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PMFBP1-to-partner and partner-to-PMFBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMFBP1 versus MICAL3_S1649 in LSCC, with a Pearson correlation of 0.49.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PMFBP1→partner) and Y-score (partner→PMFBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MICAL3_S1649 →	+0.979	+1.010	<.001	<.001	3	3
BRCA	SRRM2_S839 →	+2.267	+1.199	<.001	<.001	3	3
HNSC	MAP1S_S731 →	-0.416	-0.701	<.001	<.001	3	2
BRCA	MAP2_S1480 →	+2.290	+1.226	<.001	<.001	3	2
LSCC	INTS1_S104 →	-0.825	-0.656	<.001	<.001	3	2
LSCC	KAT7_S57 →	-0.703	-0.476	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,073 associations by consensus.

PMFBP1 vs MICAL3_S1649 — LSCC

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