PMFBP1

Across TCGA cell cohorts, PMFBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,122 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PMFBP1-associated GO terms across cancer lineages are Viral transcription, Late viral transcription, and mRNA splice site recognition. Each is linked with PMFBP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both PMFBP1-to-partner and partner-to-PMFBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral transcription grouped by PMFBP1-low versus PMFBP1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PMFBP1→partner) and Y-score (partner→PMFBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Viral transcription →	+0.115	+1.010	.002	<.001	2	17
BONE	Late viral transcription →	+0.144	+0.553	<.001	<.001	3	16
OESOPHAGUS	mRNA splice site recognition →	+0.147	+1.106	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.090	+0.710	<.001	.009	3	14
STOMACH	Negative regulation of mRNA splicing, via spliceosome →	+0.119	+0.892	.001	.007	3	13
OESOPHAGUS	Nucleic acid catabolic process →	+0.062	+0.776	.001	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,122 associations by consensus.

Viral transcription by PMFBP1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →