PMEPA1

Across TCGA cell cohorts, PMEPA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,032 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PMEPA1-associated GO terms across cancer lineages are Regulation of protein maturation, Cell-substrate adhesion, and Regulation of protein processing. Each is linked with PMEPA1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PMEPA1-to-partner and partner-to-PMEPA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein maturation grouped by PMEPA1-low versus PMEPA1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PMEPA1→partner) and Y-score (partner→PMEPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of protein maturation →	+0.171	+3.539	.001	<.001	3	15
PANCREAS	Cell-substrate adhesion →	+0.129	+2.860	<.001	<.001	3	15
LIVER	Regulation of protein processing →	+0.166	+5.451	<.001	<.001	3	15
LIVER	Wound healing →	+0.101	+4.569	<.001	<.001	3	14
OESOPHAGUS	Integrin-mediated signaling pathway →	+0.150	+2.622	.001	.004	3	14
OESOPHAGUS	Regulation of proteolysis →	+0.130	+3.190	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,032 associations by consensus.

Regulation of protein maturation by PMEPA1 expression — OESOPHAGUS

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