PMCHL2

Across TCGA patient cohorts, PMCHL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 4,872 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PMCHL2-associated proteins across cancer lineages are MAP2_S1155, PRKCE, and RAI14_S412. Each is linked with PMCHL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PMCHL2-to-partner and partner-to-PMCHL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMCHL2 versus MAP2_S1155 in PDAC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PMCHL2→partner) and Y-score (partner→PMCHL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MAP2_S1155 →	+1.059	+0.636	<.001	<.001	3	3
PDAC	PRKCE →	+0.318	+0.316	.003	.006	3	2
COAD	RAI14_S412 →	-0.355	-0.022	.001	.001	3	2
PDAC	MDM1_T515 →	+0.271	+0.395	.009	.008	3	2
CCRCC	MGAT1 →	-0.295	-0.416	.002	.004	3	2
CCRCC	NFIA_S280 →	+0.336	+0.438	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,872 associations by consensus.

PMCHL2 vs MAP2_S1155 — PDAC

Explore this scatter interactively →