PMCHL2

Across TCGA patient cohorts, PMCHL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,507 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PMCHL2-associated GO terms across cancer lineages are Regulation of organelle assembly, Positive regulation of transcription by RNA polymerase I, and Transcription initiation at RNA polymerase III promoter. Each is linked with PMCHL2 in more than 11 cancer types. Because this analysis shows association rather than direction, both PMCHL2-to-partner and partner-to-PMCHL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of organelle assembly grouped by PMCHL2-low versus PMCHL2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PMCHL2→partner) and Y-score (partner→PMCHL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of organelle assembly →	+0.062	+0.059	<.001	<.001	3	12
STAD	Positive regulation of transcription by RNA polymerase I →	+0.075	+0.065	<.001	<.001	3	12
STAD	Transcription initiation at RNA polymerase III promoter →	+0.053	+0.056	<.001	<.001	3	12
STAD	Regulation of mRNA processing →	+0.080	+0.060	<.001	<.001	3	11
STAD	Negative regulation of DNA metabolic process →	+0.054	+0.055	<.001	<.001	3	11
STAD	Regulation of mRNA catabolic process →	+0.063	+0.075	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,507 associations by consensus.

Regulation of organelle assembly by PMCHL2 expression — STAD

Explore this box plot interactively →