Across TCGA patient cohorts, PMCH protein abundance is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PMCH-associated genes across cancer lineages are PMP22, AMIGO2, and ROBO4. Each is linked with PMCH in more than 1 cancer types. Because this analysis shows association rather than direction, both PMCH-to-partner and partner-to-PMCH results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PMCH→partner) and Y-score (partner→PMCH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PMP22 →	-2.795	-0.664	.004	.002	2	1
UCEC	AMIGO2 →	-2.389	-0.664	.008	.002	2	1
UCEC	ROBO4 →	-1.290	-0.664	.009	.002	2	1
UCEC	CAVIN4 →	-0.970	-0.664	.008	.002	2	1
UCEC	GAPDHP51 →	-1.255	-0.664	.001	.002	2	1
UCEC	PCDHGC3 →	-1.844	-0.664	.006	.002	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

PMCH survival (RNA) · tumor vs normal (RNA) · all PMCH data types