PM20D2

Across TCGA patient cohorts, PM20D2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,120 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PM20D2-associated genes across cancer lineages are UBE3D, NDUFAF4, and ORC3. Each is linked with PM20D2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PM20D2-to-partner and partner-to-PM20D2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PM20D2 versus UBE3D in LSCC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PM20D2→partner) and Y-score (partner→PM20D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UBE3D →	+0.448	+0.431	<.001	<.001	3	8
LSCC	NDUFAF4 →	+0.700	+0.742	<.001	<.001	3	8
OV	ORC3 →	+0.561	+0.652	<.001	<.001	3	7
GBM	SMIM8 →	+0.449	+0.405	<.001	<.001	3	6
LSCC	MTRES1 →	+0.534	+0.450	<.001	<.001	3	6
GBM	SRSF12 →	+0.864	+0.651	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,120 associations by consensus.

PM20D2 vs UBE3D — LSCC

Explore this scatter interactively →