PM20D1

Across TCGA patient cohorts, PM20D1 mutation is significantly associated with the RNA expression of many other genes, with 2,091 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PM20D1-associated genes across cancer lineages are FBXL12P1, RN7SL717P, and DDX11-AS1. Each is linked with PM20D1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PM20D1-to-partner and partner-to-PM20D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FBXL12P1 grouped by PM20D1-low versus PM20D1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PM20D1→partner) and Y-score (partner→PM20D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	FBXL12P1 →	+0.074	+6.147	<.001	.002	3	3
SKCM	RN7SL717P →	+0.051	+3.040	<.001	.002	3	2
SKCM	DDX11-AS1 →	+0.395	+2.629	.003	.005	3	2
UCEC	DHX37 →	+0.327	+1.773	.005	.008	3	2
UCEC	GPATCH11 →	+0.353	+1.662	.004	.004	3	2
UCEC	SUPV3L1 →	+0.310	+2.627	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,091 associations by consensus.

FBXL12P1 by PM20D1 expression — BLCA

Explore this box plot interactively →