PLXNC1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PLXNC1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,434 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLXNC1-associated genes across cancer lineages are IL10RA, ARHGAP9, and DOCK2. Each is linked with PLXNC1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PLXNC1-to-partner and partner-to-PLXNC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLXNC1 versus IL10RA in HNSC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXNC1→partner) and Y-score (partner→PLXNC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCIL10RA →+1.215+0.421<.001<.00139
UCECARHGAP9 →+0.930+0.509<.001<.00139
HNSCDOCK2 →+1.105+0.406<.001<.00139
CCRCCGPR65 →+0.871+0.619<.001.00139
HNSCPIK3R5 →+1.003+0.372<.001<.00139
OVMYO1F →+1.083+0.639<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,434 associations by consensus.

PLXNC1 vs IL10RA — HNSC

Per-sample scatter of PLXNC1 vs IL10RA in HNSC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration