PLXNC1

Across TCGA cell cohorts, PLXNC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,927 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PLXNC1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Paranodal junction assembly, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with PLXNC1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PLXNC1-to-partner and partner-to-PLXNC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by PLXNC1-low versus PLXNC1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXNC1→partner) and Y-score (partner→PLXNC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.117	+0.897	<.001	.003	3	9
BREAST	Paranodal junction assembly →	-0.222	-0.518	.002	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.114	+0.897	<.001	.003	3	9
LUNG_NSCLC_LUSC	Negative regulation of organelle assembly →	+0.086	+0.803	.001	.009	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.062	+0.961	<.001	.002	3	9
STOMACH	Peptidyl-serine phosphorylation →	+0.083	+1.665	.001	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,927 associations by consensus.

Negative regulation of myoblast fusion by PLXNC1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →