Across TCGA cell cohorts, PLXNB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,870 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLXNB3-associated GO terms across cancer lineages are Negative regulation of lamellipodium assembly, Negative regulation of protein catabolic process, and Positive regulation of intracellular protein transport. Each is linked with PLXNB3 in more than 13 cancer types. Because this analysis shows association rather than direction, both PLXNB3-to-partner and partner-to-PLXNB3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXNB3→partner) and Y-score (partner→PLXNB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of lamellipodium assembly →	-0.327	-2.748	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of protein catabolic process →	+0.060	+1.363	.004	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular protein transport →	+0.073	+1.145	.003	.001	3	13
BONE	Positive regulation of intracellular transport →	+0.066	+1.461	<.001	.002	3	13
BONE	Assembly of actomyosin apparatus involved in cytokinesis →	+0.261	+2.465	<.001	<.001	3	12
BONE	Actomyosin contractile ring assembly →	+0.261	+2.465	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,870 associations by consensus.

Exploration

PLXNB3 survival (RNA) · tumor vs normal (RNA) · all PLXNB3 data types