Across TCGA cell cohorts, PLXNA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,015 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLXNA4-associated GO terms across cancer lineages are Hypothalamus cell differentiation, Negative regulation of organelle assembly, and Positive regulation of protein localization to mitochondrion. Each is linked with PLXNA4 in more than 7 cancer types. Because this analysis shows association rather than direction, both PLXNA4-to-partner and partner-to-PLXNA4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXNA4→partner) and Y-score (partner→PLXNA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Hypothalamus cell differentiation →	+0.161	+0.402	.007	<.001	3	8
CNS	Negative regulation of organelle assembly →	+0.044	+0.906	<.001	.002	3	7
LUNG_NSCLC_LUAD	Positive regulation of protein localization to mitochondrion →	+0.051	+0.426	.002	<.001	3	7
BONE	Dermatan sulfate proteoglycan metabolic process →	+0.114	+0.749	<.001	.002	3	7
BONE	Coronary artery morphogenesis →	+0.378	+1.270	<.001	.001	3	7
BONE	Positive regulation of blood pressure by epinephrine-norepinephrine →	+0.758	+1.308	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,015 associations by consensus.

Exploration

PLXNA4 survival (RNA) · tumor vs normal (RNA) · all PLXNA4 data types