PLXNA3

Across TCGA patient cohorts, PLXNA3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,266 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLXNA3-associated genes across cancer lineages are PKIA, MEIS3, and BEND5. Each is linked with PLXNA3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PLXNA3-to-partner and partner-to-PLXNA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLXNA3 versus PKIA in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXNA3→partner) and Y-score (partner→PLXNA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PKIA →	+1.288	+0.483	.001	.008	3	3
BRCA	MEIS3 →	+1.059	+0.617	<.001	<.001	3	3
LSCC	BEND5 →	+1.134	+0.648	.004	<.001	3	3
BRCA	ZBED2 →	-0.819	-0.474	.001	.004	3	3
OV	HTATSF1 →	+0.653	+0.667	<.001	<.001	3	2
OV	IDS →	+0.548	+0.468	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,266 associations by consensus.

PLXNA3 vs PKIA — LSCC

Explore this scatter interactively →