PLXNA3

Across TCGA cell cohorts, PLXNA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,471 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLXNA3-associated GO terms across cancer lineages are Olfactory nerve development, Gonadotrophin-releasing hormone neuronal migration to the hypothalamus, and Hypothalamus cell migration. Each is linked with PLXNA3 in more than 18 cancer types. Because this analysis shows association rather than direction, both PLXNA3-to-partner and partner-to-PLXNA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Olfactory nerve development grouped by PLXNA3-low versus PLXNA3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXNA3→partner) and Y-score (partner→PLXNA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Olfactory nerve development →	+0.916	+1.613	<.001	.002	3	19
BLOOD_Leukemia	Gonadotrophin-releasing hormone neuronal migration to the hypothalamus →	+0.804	+0.871	<.001	<.001	3	16
LUNG_SCLC	Hypothalamus cell migration →	+0.826	+1.240	<.001	<.001	3	16
BLOOD_Leukemia	Hypothalamic tangential migration using cell-axon interactions →	+0.804	+0.871	<.001	<.001	3	16
BLOOD_Leukemia	Hypothalamus gonadotrophin-releasing hormone neuron differentiation →	+0.804	+0.871	<.001	<.001	3	16
BLOOD_Leukemia	Hypothalamus gonadotrophin-releasing hormone neuron development →	+0.804	+0.871	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,471 associations by consensus.

Olfactory nerve development by PLXNA3 expression — BONE

Explore this box plot interactively →