PLXDC1

Across TCGA patient cohorts, PLXDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,377 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLXDC1-associated genes across cancer lineages are ADGRL4, BCL6B, and CD34. Each is linked with PLXDC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PLXDC1-to-partner and partner-to-PLXDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLXDC1 versus ADGRL4 in GBM, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXDC1→partner) and Y-score (partner→PLXDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ADGRL4 →	+0.916	+0.444	<.001	<.001	3	5
CCRCC	BCL6B →	+1.073	+0.495	.002	<.001	3	5
CCRCC	CD34 →	+0.832	+0.503	<.001	<.001	3	5
BRCA	CLEC11A →	+1.085	+0.365	<.001	<.001	3	4
BRCA	FHL5 →	+0.819	+0.421	.002	.005	3	4
OV	CNRIP1 →	+1.009	+0.422	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,377 associations by consensus.

PLXDC1 vs ADGRL4 — GBM

Explore this scatter interactively →