PLXDC1

Across TCGA cell cohorts, PLXDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,938 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLXDC1-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Regulation of myoblast fusion, and Cytoskeleton-dependent cytokinesis. Each is linked with PLXDC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PLXDC1-to-partner and partner-to-PLXDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by PLXDC1-low versus PLXDC1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXDC1→partner) and Y-score (partner→PLXDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.101	+0.981	<.001	<.001	3	10
OESOPHAGUS	Regulation of myoblast fusion →	+0.106	+1.013	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Cytoskeleton-dependent cytokinesis →	+0.089	+0.912	.004	.001	3	9
BREAST	Mitotic cytokinesis →	+0.080	+0.693	.002	.002	3	9
OESOPHAGUS	Regulation of macroautophagy →	+0.083	+1.076	<.001	.001	3	9
LUNG_NSCLC_LUSC	Cell division →	+0.074	+0.674	.005	.009	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,938 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by PLXDC1 expression — OESOPHAGUS

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