PLVAP

Across TCGA patient cohorts, PLVAP RNA expression is significantly associated with the protein abundance of many other proteins, with 16,403 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PLVAP-associated proteins across cancer lineages are VWA1, COL15A1, and NID1. Each is linked with PLVAP in more than 8 cancer types. Because this analysis shows association rather than direction, both PLVAP-to-partner and partner-to-PLVAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLVAP versus VWA1 in CCRCC, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLVAP→partner) and Y-score (partner→PLVAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	VWA1 →	+0.642	+1.335	<.001	<.001	3	9
UCEC	COL15A1 →	+0.597	+0.522	<.001	.004	3	8
HNSC	NID1 →	+0.614	+0.591	<.001	<.001	2	9
GBM	NID2 →	+0.672	+1.040	<.001	<.001	3	8
OV	LAMB1 →	+0.553	+1.252	<.001	<.001	3	8
GBM	LAMC1 →	+0.699	+0.808	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,403 associations by consensus.

PLVAP vs VWA1 — CCRCC

Explore this scatter interactively →