PLVAP

Across TCGA patient cohorts, PLVAP protein abundance is significantly associated with the RNA expression of many other genes, with 19,960 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PLVAP-associated genes across cancer lineages are ASPA, FHL5, and CLEC14A. Each is linked with PLVAP in more than 8 cancer types. Because this analysis shows association rather than direction, both PLVAP-to-partner and partner-to-PLVAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLVAP versus ASPA in CCRCC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLVAP→partner) and Y-score (partner→PLVAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ASPA →	+1.039	+0.603	.003	.003	3	9
HNSC	FHL5 →	+0.929	+0.340	<.001	<.001	3	9
CCRCC	CLEC14A →	+1.192	+0.836	<.001	<.001	3	9
CCRCC	FAM162B →	+0.883	+0.769	<.001	<.001	3	9
CCRCC	ARHGEF15 →	+0.813	+0.702	<.001	<.001	3	9
CCRCC	ITGA8 →	+1.186	+0.958	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,960 associations by consensus.

PLVAP vs ASPA — CCRCC

Explore this scatter interactively →