PLVAP

Across TCGA cell cohorts, PLVAP RNA expression is significantly associated with the go_rna of many other GO terms, with 1,142 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLVAP-associated GO terms across cancer lineages are Positive regulation of autophagy, Positive regulation of signal transduction by p53 class mediator, and Regulation of cytokine-mediated signaling pathway. Each is linked with PLVAP in more than 4 cancer types. Because this analysis shows association rather than direction, both PLVAP-to-partner and partner-to-PLVAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of autophagy grouped by PLVAP-low versus PLVAP-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLVAP→partner) and Y-score (partner→PLVAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of autophagy →	+0.028	+0.515	.001	.001	3	4
URINARY_TRACT	Positive regulation of signal transduction by p53 class mediator →	+0.073	+0.071	.002	.004	2	5
LUNG_NSCLC_LUAD	Regulation of cytokine-mediated signaling pathway →	+0.031	+0.058	.006	.006	3	4
LUNG_NSCLC_LUAD	Regulation of response to cytokine stimulus →	+0.039	+0.082	.005	.009	3	4
BLOOD_Leukemia	Regulation of neurofibrillary tangle assembly →	+0.148	+1.977	<.001	<.001	3	4
BLOOD_Leukemia	Leptin-mediated signaling pathway →	+0.073	+1.662	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,142 associations by consensus.

Positive regulation of autophagy by PLVAP expression — BLOOD_Lymphoma

Explore this box plot interactively →