PLUT

Across TCGA pan-cancer cohorts, PLUT RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PLUT data layer.

The strongest signal is observed in thymoma (THYM), where higher PLUT RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PLUT expression acts as an unfavorable survival marker, although some lineages such as STAD and OV show a favorable association.

THYM, UCEC, and LIHC are the cancer types where PLUT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	All	0.718	0.974	<.001	90	view →
UCEC	OS	Tertile	IV	0.343	0.801	.001	84	view →
LIHC	DFS	Quartile	III,IV	0.103	0.245	.001	52	view →
LUAD	DFS	Quartile	III,IV	0.147	0.383	.001	46	view →
KIRC	DFS	Tertile	II,III,IV	0.223	0.532	.008	36	view →
BLCA	DFS	Median	II,III,IV	0.256	0.382	.008	35	view →
ESCA	OS	Quartile	All	0.442	1.000	.003	33	view →
STAD	OS	Quartile	All	0.738	0.574	.022	25	view →
LUSC	DFS	Quartile	III,IV	0.385	0.687	.001	25	view →
KIRP	OS	Tertile	III,IV	0.111	0.697	<.001	21	view →
OV	OS	Tertile	III,IV	0.501	0.305	.020	18	view →
PCPG	DFS	Tertile	All	0.091	0.828	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PLUT–THYM (OS)

Open the THYM breakdown →