PLSCR5

Across TCGA patient cohorts, PLSCR5 mutation is significantly associated with the RNA expression of many other genes, with 1,057 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLSCR5-associated genes across cancer lineages are ITGA9, RNA5SP461, and RNU7-110P. Each is linked with PLSCR5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLSCR5-to-partner and partner-to-PLSCR5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITGA9 grouped by PLSCR5-low versus PLSCR5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLSCR5→partner) and Y-score (partner→PLSCR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ITGA9 →	-0.933	-3.983	<.001	<.001	3	2
SKCM	RNA5SP461 →	+0.390	+7.816	<.001	<.001	3	2
SKCM	RNU7-110P →	+0.808	+4.324	<.001	.007	3	2
LUSC	LINC01869 →	+0.406	+3.229	.008	.009	3	2
UCEC	BNIP3P1 →	+0.471	+2.681	<.001	.004	3	2
UCEC	LINC01936 →	-0.428	-2.796	.009	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,057 associations by consensus.

ITGA9 by PLSCR5 expression — UCEC

Explore this box plot interactively →