PLSCR5

Across TCGA cell cohorts, PLSCR5 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PLSCR5-associated genes across cancer lineages are OR2L5, TFDP3, and NEXMIF. Each is linked with PLSCR5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLSCR5-to-partner and partner-to-PLSCR5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2L5 grouped by PLSCR5-low versus PLSCR5-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLSCR5→partner) and Y-score (partner→PLSCR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR2L5 →	+0.012	+4.887	.001	.009	3	1
LARGE_INTESTINE	TFDP3 →	+0.020	+3.196	.001	.007	3	1
LARGE_INTESTINE	NEXMIF →	+0.283	+3.196	<.001	.007	3	1
LARGE_INTESTINE	VAX1 →	+0.771	+3.519	<.001	.007	2	1
LARGE_INTESTINE	CEACAM20 →	+0.189	+3.700	<.001	.008	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR2L5 by PLSCR5 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →