PLSCR4

Across TCGA pan-cancer cohorts, PLSCR4 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PLSCR4 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher PLSCR4 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PLSCR4 expression acts as an unfavorable survival marker.

PDAC, LSCC, and GBM are the cancer types where PLSCR4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	II,III,IV	0.555	0.873	.003	26	view →
LSCC	DFS	Tertile	III,IV	0.563	1.000	.031	7	view →
GBM	DFS	Tertile	All	0.254	0.498	.025	5	view →
LUAD	DFS	Tertile	II,III,IV	0.673	0.985	.005	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PLSCR4–PDAC (DFS)

Open the PDAC breakdown →