Across TCGA patient cohorts, PLSCR3 mutation is significantly associated with the RNA expression of many other genes, with 233 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLSCR3-associated genes across cancer lineages are POLR2KP2, LINC01758, and LINC01327. Each is linked with PLSCR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLSCR3-to-partner and partner-to-PLSCR3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLSCR3→partner) and Y-score (partner→PLSCR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POLR2KP2 →	+0.224	+3.136	<.001	.007	3	2
UCEC	LINC01758 →	+0.172	+2.871	.001	.002	3	2
UCEC	LINC01327 →	+0.138	+3.175	.002	.002	3	2
UCEC	RNU6-162P →	+0.163	+5.308	<.001	.001	3	2
UCEC	MTUS2-AS1 →	+0.375	+3.610	<.001	.003	3	1
UCEC	LINC00482 →	+0.692	+3.322	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 233 associations by consensus.

Exploration

PLSCR3 survival (RNA) · tumor vs normal (RNA) · all PLSCR3 data types