PLSCR2

Across TCGA patient cohorts, PLSCR2 mutation is significantly associated with the RNA expression of many other genes, with 1,958 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLSCR2-associated genes across cancer lineages are CBARP, JOSD1, and MEX3D. Each is linked with PLSCR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PLSCR2-to-partner and partner-to-PLSCR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBARP grouped by PLSCR2-low versus PLSCR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLSCR2→partner) and Y-score (partner→PLSCR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CBARP →	+0.704	+3.459	<.001	<.001	3	3
SKCM	JOSD1 →	+0.579	+2.745	<.001	.003	3	3
SKCM	MEX3D →	+0.844	+3.331	<.001	.005	3	3
UCEC	HAUS2 →	+0.588	+2.321	<.001	.001	3	3
UCEC	PGAP2 →	+0.382	+1.922	.003	.009	3	2
UCEC	ZDHHC5 →	+0.273	+2.246	.008	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,958 associations by consensus.

CBARP by PLSCR2 expression — UCEC

Explore this box plot interactively →