PLSCR1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PLSCR1 mutation is significantly associated with the RNA expression of many other genes, with 1,603 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLSCR1-associated genes across cancer lineages are CXCL1P1, RNA5SP414, and OR2AP1. Each is linked with PLSCR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLSCR1-to-partner and partner-to-PLSCR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLSCR1→partner) and Y-score (partner→PLSCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCXCL1P1 →+0.353+5.145<.001.00732
UCECRNA5SP414 →+0.497+2.255.001.00932
LUADOR2AP1 →+0.053+5.584<.001.00232
LUADRNU6-380P →+0.359+6.333<.001<.00132
UCECRNA5SP419 →+0.526+2.492.003.00232
LUSCRAB11AP1 →+0.118+3.890<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,603 associations by consensus.

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