PLSCR1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PLSCR1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PLSCR1-associated genes across cancer lineages are INSL5, OR10W1, and ABCG8. Each is linked with PLSCR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLSCR1-to-partner and partner-to-PLSCR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLSCR1→partner) and Y-score (partner→PLSCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEINSL5 →+0.385+3.626<.001.00631
LARGE_INTESTINEOR10W1 →+0.016+3.977<.001.00131
LARGE_INTESTINEABCG8 →+0.371+3.453<.001.00921
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

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