PLPPR5

Across TCGA cell cohorts, PLPPR5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,087 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PLPPR5-associated GO terms across cancer lineages are Actin filament depolymerization, Telomere tethering at nuclear periphery, and Amacrine cell differentiation. Each is linked with PLPPR5 in more than 3 cancer types. Because this analysis shows association rather than direction, both PLPPR5-to-partner and partner-to-PLPPR5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament depolymerization grouped by PLPPR5-low versus PLPPR5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPPR5→partner) and Y-score (partner→PLPPR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Actin filament depolymerization →	+0.108	+0.097	.001	.003	3	4
SKIN	Telomere tethering at nuclear periphery →	+0.054	+0.437	<.001	.002	3	4
CNS	Amacrine cell differentiation →	+0.936	+0.719	<.001	.008	3	4
SKIN	Regulation of metaphase plate congression →	+0.112	+0.663	.004	.004	3	4
SOFT_TISSUE	Negative regulation of antigen processing and presentation of peptide antigen →	-0.658	-0.143	.005	.001	3	4
SKIN	Lateral ventricle development →	+0.100	+0.565	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,087 associations by consensus.

Actin filament depolymerization by PLPPR5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →