PLPPR4

Across TCGA cell cohorts, PLPPR4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,653 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLPPR4-associated GO terms across cancer lineages are Endosomal transport, Positive regulation of intracellular transport, and Negative regulation of calcineurin-NFAT signaling cascade. Each is linked with PLPPR4 in more than 5 cancer types. Because this analysis shows association rather than direction, both PLPPR4-to-partner and partner-to-PLPPR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by PLPPR4-low versus PLPPR4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPPR4→partner) and Y-score (partner→PLPPR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.076	+0.071	<.001	.005	3	6
BONE	Positive regulation of intracellular transport →	+0.068	+1.453	<.001	.004	3	6
BONE	Negative regulation of calcineurin-NFAT signaling cascade →	+0.233	+1.038	<.001	.003	3	6
BONE	Negative regulation of calcineurin-mediated signaling →	+0.233	+1.038	<.001	.003	3	6
BONE	Retrograde transport, endosome to Golgi →	+0.060	+1.109	<.001	.002	3	6
UPPER_AERODIGESTIVE_TRACT	Protein-containing complex disassembly →	+0.104	+0.078	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,653 associations by consensus.

Endosomal transport by PLPPR4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →