PLPPR3

Across TCGA patient cohorts, PLPPR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,488 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLPPR3-associated proteins across cancer lineages are PDIA6, RPGR_S518, and HSDL1. Each is linked with PLPPR3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PLPPR3-to-partner and partner-to-PLPPR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLPPR3 versus PDIA6 in BRCA, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPPR3→partner) and Y-score (partner→PLPPR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PDIA6 →	-0.336	-1.331	<.001	<.001	3	3
UCEC	RPGR_S518 →	+0.715	+1.203	<.001	<.001	3	3
GBM	HSDL1 →	+0.373	+1.104	<.001	<.001	3	3
UCEC	IFT122 →	+0.395	+0.998	<.001	<.001	3	3
UCEC	IFT140 →	+0.401	+0.981	<.001	<.001	3	3
UCEC	IFT172 →	+0.359	+0.988	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,488 associations by consensus.

PLPPR3 vs PDIA6 — BRCA

Explore this scatter interactively →