PLPPR2

Across TCGA patient cohorts, PLPPR2 mutation is significantly associated with the RNA expression of many other genes, with 1,687 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLPPR2-associated genes across cancer lineages are RNU6-471P, RNA5SP19, and HSPA8P17. Each is linked with PLPPR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PLPPR2-to-partner and partner-to-PLPPR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-471P grouped by PLPPR2-low versus PLPPR2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPPR2→partner) and Y-score (partner→PLPPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-471P →	+0.308	+7.640	<.001	.009	3	3
BRCA	RNA5SP19 →	+0.300	+4.479	<.001	.007	3	2
BRCA	HSPA8P17 →	+0.034	+5.365	<.001	.002	3	2
BRCA	RN7SL824P →	+0.252	+4.153	<.001	.004	3	2
BRCA	MTND6P17 →	+0.058	+5.281	<.001	.002	3	2
UCEC	MIR572 →	+0.165	+3.885	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,687 associations by consensus.

RNU6-471P by PLPPR2 expression — BLCA

Explore this box plot interactively →