PLPPR2

Across TCGA cell cohorts, PLPPR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,467 significant associations in total. CNS shows the largest number of these associations.

The most reproducible PLPPR2-associated GO terms across cancer lineages are Regulation of glycolytic process through fructose-6-phosphate, Negative regulation of glycolytic process through fructose-6-phosphate, and Positive regulation of macroautophagy. Each is linked with PLPPR2 in more than 13 cancer types. Because this analysis shows association rather than direction, both PLPPR2-to-partner and partner-to-PLPPR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of glycolytic process through fructose-6-phosphate grouped by PLPPR2-low versus PLPPR2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPPR2→partner) and Y-score (partner→PLPPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of glycolytic process through fructose-6-phosphate →	+0.144	+1.543	<.001	.004	3	14
OESOPHAGUS	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.144	+1.543	<.001	.004	3	14
STOMACH	Positive regulation of macroautophagy →	+0.064	+1.783	.002	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.069	+1.816	<.001	<.001	3	13
LUNG_SCLC	COPI-coated vesicle budding →	+0.127	+1.506	<.001	.001	3	13
LUNG_SCLC	Golgi transport vesicle coating →	+0.127	+1.506	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,467 associations by consensus.

Regulation of glycolytic process through fructose-6-phosphate by PLPPR2 expression — OESOPHAGUS

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