PLPPR1

Across TCGA patient cohorts, PLPPR1 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,210 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLPPR1-associated proteins across cancer lineages are BIN2_S425, ARNTL, and ARPP19. Each is linked with PLPPR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLPPR1-to-partner and partner-to-PLPPR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLPPR1 versus BIN2_S425 in GBM, with a Pearson correlation of -0.38.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPPR1→partner) and Y-score (partner→PLPPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BIN2_S425 →	-0.814	-0.822	<.001	.001	2	2
GBM	ARNTL →	-0.389	-0.812	<.001	<.001	3	1
GBM	ARPP19 →	+0.236	+0.599	.002	.002	3	1
GBM	ASTN1_S376 →	+0.388	+0.595	.001	.002	3	1
GBM	ATG2B →	+0.244	+0.873	<.001	<.001	3	1
GBM	ATM_T1885 →	-0.590	-0.804	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,210 associations by consensus.

PLPPR1 vs BIN2_S425 — GBM

Explore this scatter interactively →