PLPPR1

Across TCGA patient cohorts, PLPPR1 mutation is significantly associated with the RNA expression of many other genes, with 2,923 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLPPR1-associated genes across cancer lineages are RN7SL393P, RNA5SP410, and RNA5SP414. Each is linked with PLPPR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PLPPR1-to-partner and partner-to-PLPPR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL393P grouped by PLPPR1-low versus PLPPR1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPPR1→partner) and Y-score (partner→PLPPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL393P →	+0.073	+2.684	<.001	.004	3	3
UCEC	RNA5SP410 →	+0.463	+1.724	<.001	.001	3	3
UCEC	RNA5SP414 →	+0.341	+1.554	.001	.009	3	2
BRCA	RNA5SP416 →	+0.482	+7.471	<.001	.008	3	2
UCEC	VTI1B →	+0.400	+1.700	<.001	.002	3	2
UCEC	SEC23A →	+0.402	+1.522	.007	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,923 associations by consensus.

RN7SL393P by PLPPR1 expression — SKCM

Explore this box plot interactively →