PLPPR1

Across TCGA cell cohorts, PLPPR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,512 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PLPPR1-associated GO terms across cancer lineages are External encapsulating structure organization, Regulation of interleukin-1 production, and Extracellular matrix organization. Each is linked with PLPPR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLPPR1-to-partner and partner-to-PLPPR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, External encapsulating structure organization grouped by PLPPR1-low versus PLPPR1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPPR1→partner) and Y-score (partner→PLPPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	External encapsulating structure organization →	-0.067	-0.100	<.001	.001	3	7
LUNG_SCLC	Regulation of interleukin-1 production →	-0.079	-1.911	.003	.004	3	6
OVARY	Extracellular matrix organization →	-0.066	-0.103	<.001	<.001	3	6
OVARY	Regulation of interleukin-1 beta production →	-0.075	-0.089	<.001	.004	3	6
LUNG_NSCLC_LUSC	Oncostatin-M-mediated signaling pathway →	-0.251	-0.894	<.001	<.001	3	6
OVARY	Extracellular structure organization →	-0.067	-0.100	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,512 associations by consensus.

External encapsulating structure organization by PLPPR1 expression — OVARY

Explore this box plot interactively →