Across TCGA patient cohorts, PLPP6 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,408 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLPP6-associated proteins across cancer lineages are PLGRKT, RANBP6, and CDC37L1. Each is linked with PLPP6 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLPP6-to-partner and partner-to-PLPP6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPP6→partner) and Y-score (partner→PLPP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLGRKT →	+0.549	+0.427	<.001	<.001	3	7
GBM	RANBP6 →	+0.363	+0.584	<.001	<.001	3	7
OV	CDC37L1 →	+0.528	+0.749	<.001	<.001	3	6
LSCC	UHRF2 →	+0.407	+0.486	<.001	<.001	3	5
LSCC	ERMP1 →	+0.590	+0.492	<.001	<.001	3	5
UCEC	STX17 →	+0.269	+0.478	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,408 associations by consensus.

Exploration

PLPP6 survival (RNA) · tumor vs normal (RNA) · all PLPP6 data types