Across TCGA cell cohorts, PLPP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,483 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLPP6-associated GO terms across cancer lineages are Positive regulation of neutrophil activation, Prenylation, and Protein prenylation. Each is linked with PLPP6 in more than 16 cancer types. Because this analysis shows association rather than direction, both PLPP6-to-partner and partner-to-PLPP6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPP6→partner) and Y-score (partner→PLPP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of neutrophil activation →	+1.512	+0.968	<.001	<.001	3	17
OVARY	Prenylation →	+0.139	+1.025	<.001	<.001	3	14
OVARY	Protein prenylation →	+0.139	+1.025	<.001	<.001	3	14
KIDNEY	Regulation of syncytium formation by plasma membrane fusion →	+0.099	+0.589	.004	.007	2	12
KIDNEY	Regulation of myoblast fusion →	+0.091	+0.634	.007	.003	3	11
BONE	ITP metabolic process →	+0.085	+1.609	.006	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,483 associations by consensus.

Exploration

PLPP6 survival (RNA) · tumor vs normal (RNA) · all PLPP6 data types