Across TCGA patient cohorts, PLPP4 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLPP4-associated genes across cancer lineages are Th2 cells, Endothelial cells, and Mesangial cells. Each is linked with PLPP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLPP4-to-partner and partner-to-PLPP4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPP4→partner) and Y-score (partner→PLPP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Th2 cells →	+0.284	+3.000	.006	.037	2	1
UCEC	Endothelial cells →	-0.053	-2.957	.017	.037	1	1
UCEC	Mesangial cells →	-0.057	-2.989	.010	.037	1	1
UCEC	mv Endothelial cells →	-0.039	-2.989	.004	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

PLPP4 survival (RNA) · tumor vs normal (RNA) · all PLPP4 data types