Across TCGA cell cohorts, PLPP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,972 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLPP4-associated GO terms across cancer lineages are Protein lipidation, Regulation of plasminogen activation, and Negative regulation of plasminogen activation. Each is linked with PLPP4 in more than 11 cancer types. Because this analysis shows association rather than direction, both PLPP4-to-partner and partner-to-PLPP4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPP4→partner) and Y-score (partner→PLPP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Protein lipidation →	+0.185	+4.713	<.001	<.001	3	12
SOFT_TISSUE	Regulation of plasminogen activation →	+0.283	+2.694	<.001	<.001	3	11
BONE	Negative regulation of plasminogen activation →	+0.939	+2.300	.006	.001	3	11
LUNG_NSCLC_LUSC	Peptidyl-lysine oxidation →	+1.642	+2.360	<.001	<.001	3	10
SOFT_TISSUE	Lipoprotein metabolic process →	+0.084	+2.059	<.001	<.001	3	9
SOFT_TISSUE	Regulation of collagen biosynthetic process →	+0.152	+2.079	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,972 associations by consensus.

Exploration

PLPP4 survival (RNA) · tumor vs normal (RNA) · all PLPP4 data types