PLPP2

Across TCGA patient cohorts, PLPP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,268 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLPP2-associated proteins across cancer lineages are ARFGEF3, CAPS, and PPM1H. Each is linked with PLPP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PLPP2-to-partner and partner-to-PLPP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLPP2 versus ARFGEF3 in CCRCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPP2→partner) and Y-score (partner→PLPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ARFGEF3 →	+0.554	+0.955	.002	.002	3	6
OV	CAPS →	+0.937	+1.016	<.001	<.001	3	5
GBM	PPM1H →	+0.757	+0.837	<.001	.004	3	5
GBM	PPM1H_S124 →	+0.814	+0.890	<.001	.002	3	5
UCEC	RFTN1 →	-0.455	-0.826	<.001	.002	3	5
HNSC	TRIM2 →	+0.566	+0.744	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,268 associations by consensus.

PLPP2 vs ARFGEF3 — CCRCC

Explore this scatter interactively →