PLPP2

Across TCGA patient cohorts, PLPP2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,356 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLPP2-associated genes across cancer lineages are LRCH2, ABI3BP, and TNFAIP6. Each is linked with PLPP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PLPP2-to-partner and partner-to-PLPP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLPP2 versus LRCH2 in OV, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPP2→partner) and Y-score (partner→PLPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LRCH2 →	-1.050	-1.179	<.001	<.001	3	4
UCEC	ABI3BP →	-1.207	-0.676	<.001	<.001	3	4
UCEC	TNFAIP6 →	-1.276	-0.935	<.001	<.001	3	4
OV	CDH23 →	-0.603	-0.584	<.001	.006	3	3
OV	ELAPOR1 →	+1.663	+0.825	.006	.001	3	3
UCEC	ACOXL →	-0.753	-1.018	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,356 associations by consensus.

PLPP2 vs LRCH2 — OV

Explore this scatter interactively →